ProTAME
ProTAME is an APC/C inhibitor that synergizes with topoisomerase II inhibitors like doxorubicin to enhance cell death, particularly in Multiple Myeloma models, by first elevating TOPIIα levels. Its application in cancer research includes in vitro studies on cell cycle arrest and apoptosis, though its instability necessitates the use of stabilized salt forms.
Product Specifications
CAS Number
1362911-19-0
Field of Research
Cell Biology
Smiles
COC (=O) [C@H] (CCCN=C (NC (=O) OCOC (=O) Cc1ccccc1) NC (=O) OCOC (=O) Cc1ccccc1) NS (=O) (=O) c1ccc (C) cc1
Molecular Formula
C34H38N4O12S
Molecular Weight
726.75
Storage Conditions
-20°C
Notes
For research use only.
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