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R-1663

R-1663 is a selective factor Xa inhibitor that prolongs clotting times and suppresses thrombin generation in a concentration-dependent manner, with a greater effect on peak thrombin (IC50 194 ng/mL) than on endogenous thrombin potential. It is used in research applications for studying anticoagulant mechanisms and thrombosis models in vitro and in vivo, without prolonging bleeding time at effective concentrations.

Product Specifications

CAS Number

865451-66-7

Field of Research

Metabolism Research

Smiles

C (NC1=C (F) C=C (C=C1) N2C (=O) C=CC=C2) (=O) [C@@H]3[C@@H] (C (NC4=CC=C (Cl) C=N4) =O) CN (CC (F) F) C3

Molecular Formula

C24H21ClF3N5O3

Molecular Weight

519.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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