RA-839
RA-839 is a selective small molecule activator of Nrf2 signaling that functions by covalently binding to Keap1 and disrupting the Keap1-Nrf2 interaction. It demonstrates anticancer activity and has been shown in research to suppress inducible nitric oxide synthase expression and nitric oxide production in both cellular and animal models of oxidative stress and inflammation.
Product Specifications
CAS Number
1832713-02-6
Product Name Alternative
RA 839, RA839, RA-839, KEAP1-Nrf2
Field of Research
Immunology & Inflammation
Purity
98.38% (May vary between batches)
Solubility
DMSO:80 mg/mL (176.77 mM)
Smiles
Cc1cc (C) c (C) c (c1C) S (=O) (=O) Nc1ccc (N2CC[C@@H] (C2) C (O) =O) c2ccccc12
Molecular Formula
C25H28N2O4S
Molecular Weight
452.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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