REDX05358
REDX05358 is a potent and highly selective pan-RAF inhibitor with subnanomolar affinity for BRAF and CRAF. It effectively suppresses both RAF monomers and dimers, minimizing paradoxical activation, and shows promise for researching BRAF- and RAS-mutant cancers in cellular and animal models.
Product Specifications
CAS Number
1884226-20-3
Field of Research
Signal Transduction
Smiles
O (C=1C=C2C (OCC (C2) C=3NC (=CN3) C4=C (Cl) C=CC=C4) =CC1) C5=C6C (NC=C5) =NC (=O) CC6
Molecular Formula
C26H21ClN4O3
Molecular Weight
472.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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