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REDX05358

REDX05358 is a potent and highly selective pan-RAF inhibitor with subnanomolar affinity for BRAF and CRAF. It effectively suppresses both RAF monomers and dimers, minimizing paradoxical activation, and shows promise for researching BRAF- and RAS-mutant cancers in cellular and animal models.

Product Specifications

CAS Number

1884226-20-3

Field of Research

Signal Transduction

Smiles

O (C=1C=C2C (OCC (C2) C=3NC (=CN3) C4=C (Cl) C=CC=C4) =CC1) C5=C6C (NC=C5) =NC (=O) CC6

Molecular Formula

C26H21ClN4O3

Molecular Weight

472.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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