Ro 41-5253
Ro 41-5253 is a synthetic small molecule functioning as an RARα antagonist and a PPARγ ligand/partial agonist. It demonstrates anti-proliferative and pro-apoptotic effects in estrogen receptor-positive breast cancer cell lines like MCF-7 and ZR-75.1, making it a useful research tool for studying nuclear receptor signaling in oncology.
Product Specifications
CAS Number
144092-31-9
Field of Research
Cell Biology, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
RARα antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 12 mg/ml with warming)
Smiles
CCCCCCCOc1cc2c (cc1\C (C) =C\c1ccc (cc1) C (O) =O) C (C) (C) CCS2 (=O) =O
Molecular Formula
C28H36O5S
Molecular Weight
484.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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