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Ro 41-5253

Ro 41-5253 is a synthetic small molecule functioning as an RARα antagonist and a PPARγ ligand/partial agonist. It demonstrates anti-proliferative and pro-apoptotic effects in estrogen receptor-positive breast cancer cell lines like MCF-7 and ZR-75.1, making it a useful research tool for studying nuclear receptor signaling in oncology.

Product Specifications

CAS Number

144092-31-9

Field of Research

Cell Biology, Neuroscience, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

RARα antagonist

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 12 mg/ml with warming)

Smiles

CCCCCCCOc1cc2c (cc1\C (C) =C\c1ccc (cc1) C (O) =O) C (C) (C) CCS2 (=O) =O

Molecular Formula

C28H36O5S

Molecular Weight

484.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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