S39625
S39625 is a stable, potent, and selective topoisomerase I inhibitor that evades drug efflux transporters. It induces persistent DNA damage (γ-H2AX) and Top1 cleavage complexes at nanomolar concentrations, demonstrating potent antiproliferative activity in cancer cell lines, supporting its investigation as an anticancer agent in both in vitro and in vivo research.
Product Specifications
CAS Number
536711-20-3
Field of Research
Molecular Biology
Smiles
O=C1N2CC=3C (C2=CC4=C1CC (=O) C4 (CC) O) =NC=5C (C3C6CCC6) =CC7=C (C5) OCO7
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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