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SB220025

SB220025 is a potent, orally bioavailable, and selective p38 MAPK inhibitor that also suppresses p56Lck and PKC activity. It disrupts endothelial growth hormone-induced calcium signaling and angiogenesis, making it a valuable compound for studying inflammatory diseases such as arthritis in both cellular and animal models.

Product Specifications

CAS Number

165806-53-1

Product Name Alternative

SB 220025, SB220025, SB-220025

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction

Purity

99.44% (May vary between batches)

Solubility

DMSO:100 mg/mL (295.53 mM)

Smiles

FC1=CC=C (C=C1) C=2N=CN (C2C=3N=C (N=CC3) N) C4CCNCC4

Molecular Formula

C18H19FN6

Molecular Weight

338.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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