SB-747651A
SB-747651A is a potent and selective ATP-competitive inhibitor of MSK1 (IC50 = 11 nM) that targets its N-terminal kinase domain. This compound also inhibits related kinases including MSK2, PKA, PKB, RSK, and p70S6K in cellular assays, making it a valuable tool for studying kinase signaling pathways in inflammation, cancer, and neurological research.
Product Specifications
CAS Number
607372-46-3
Field of Research
Signal Transduction
Smiles
C (C) N1C=2C (N=C1C=3C (N) =NON3) =CN=CC2CNC4CCNCC4
Molecular Formula
C16H22N8O
Molecular Weight
342.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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