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SC-2001

SC-2001 is a small molecule MCL-1 inhibitor that induces apoptosis in breast cancer cells by blocking STAT3 phosphorylation via SHP-1 upregulation. It also overcomes STAT3-mediated sorafenib resistance in hepatocellular carcinoma through RFX-1/SHP-1 activation, as demonstrated in in vitro studies.

Product Specifications

CAS Number

1383727-17-0

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

C (C=1NC (C2=CC=3C (N2) =CC=C (Br) C3) =CC1OC) =C4C=CC=N4

Molecular Formula

C18H14BrN3O

Molecular Weight

368.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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