SC-2001
SC-2001 is a small molecule MCL-1 inhibitor that induces apoptosis in breast cancer cells by blocking STAT3 phosphorylation via SHP-1 upregulation. It also overcomes STAT3-mediated sorafenib resistance in hepatocellular carcinoma through RFX-1/SHP-1 activation, as demonstrated in in vitro studies.
Product Specifications
CAS Number
1383727-17-0
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (C=1NC (C2=CC=3C (N2) =CC=C (Br) C3) =CC1OC) =C4C=CC=N4
Molecular Formula
C18H14BrN3O
Molecular Weight
368.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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