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Setrobuvir

Setrobuvir (ANA-598) is a potent, orally bioavailable non-nucleoside inhibitor of the HCV NS5B polymerase, effective in the low nanomolar range. It also demonstrates binding affinity and inhibitory activity against the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), supporting its investigation in antiviral research for both hepatitis C and COVID-19.

Product Specifications

CAS Number

1071517-39-9

Product Name Alternative

HCVProtease, HCV Protease, HCV NS5B polymerase, DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, ANA 598, ANA598, ANA-598, Setrobuvir, SARS-CoV-2, SARSCoV, RO 5466731, RO5466731, RO-5466731, RNASynthesis, RNA Synthesis, RG 7790, RG7790, RG-7790

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Purity

98.92% (May vary between batches)

Solubility

DMSO:252.5 mg/mL (450.39 mM)

Smiles

C (N1[C@@]2 ([C@@] ([C@@]3 (C[C@]2 (CC3) [H]) [H]) (C (O) =C (C1=O) C=4NC=5C (S (=O) (=O) N4) =CC (NS (C) (=O) =O) =CC5) [H]) [H]) C6=CC=C (F) C=C6

Molecular Formula

C25H25FN4O6S2

Molecular Weight

560.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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