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SGE-516

SGE516 is a neuroactive steroid acting as a positive allosteric modulator of γ- and δ-subunit-containing GABAA receptors. It demonstrates anticonvulsant and neuroprotective properties, reducing neuronal firing, epileptiform activity in vitro, and acute seizures and cell death in vivo, making it a valuable research tool for studying epilepsy and neuroprotection.

Product Specifications

CAS Number

1430064-74-6

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C[C@@]12[C@] ([C@]3 ([C@] (CC1) ([C@@]4 ([C@] (CC3) (C[C@] (C) (O) CC4) [H]) [H]) [H]) [H]) (CC[C@@H]2C (CN5N=CC=N5) =O) [H]

Molecular Formula

C23H35N3O2

Molecular Weight

385.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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