SGE-516
SGE516 is a neuroactive steroid acting as a positive allosteric modulator of γ- and δ-subunit-containing GABAA receptors. It demonstrates anticonvulsant and neuroprotective properties, reducing neuronal firing, epileptiform activity in vitro, and acute seizures and cell death in vivo, making it a valuable research tool for studying epilepsy and neuroprotection.
Product Specifications
CAS Number
1430064-74-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C[C@@]12[C@] ([C@]3 ([C@] (CC1) ([C@@]4 ([C@] (CC3) (C[C@] (C) (O) CC4) [H]) [H]) [H]) [H]) (CC[C@@H]2C (CN5N=CC=N5) =O) [H]
Molecular Formula
C23H35N3O2
Molecular Weight
385.54
Storage Conditions
-20°C
Notes
For research use only.
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