SJA6017
SJA6017 is a potent, cell-permeable calpain inhibitor with selectivity for calpain-1 (IC50 = 7.5 nM) over calpain-2, and also inhibits cathepsins B and L. It has demonstrated neuroprotective effects in spinal cord injury models, reducing apoptosis, preserving tissue, and improving functional outcomes in vivo.
Product Specifications
CAS Number
190274-53-4
Field of Research
Protein Biochemistry
Smiles
S (N[C@H] (C (N[C@@H] (CC (C) C) C=O) =O) [C@@H] (C) C) (=O) (=O) C1=CC=C (F) C=C1
Molecular Formula
C17H25FN2O4S
Molecular Weight
372.45
Storage Conditions
-20°C
Notes
For research use only.
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