SK-216
SK-216 is a specific PAI-1 inhibitor that suppresses tumor angiogenesis by blocking VEGF-induced HUVEC migration and tube formation in vitro. It has also demonstrated efficacy in an in vivo model, alleviating bleomycin-induced pulmonary fibrosis in mice, highlighting its research applications in oncology and fibrotic disease.
Product Specifications
CAS Number
654080-03-2
Product Name Alternative
SK216, SK-216, SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor, SK 216
Field of Research
Metabolism Research
Purity
98.29% (May vary between batches)
Solubility
H2O:5.38 mg/mL (10.08 mM)
Smiles
O=C ([O-]) C (C ([O-]) =O) CCCCCOC1=CC2=CC=C (C=C2C=C1) C3=NC4=CC (C (C) (C) C) =CC=C4O3.[Na+].[Na+]
Molecular Formula
C29H29NNa2O6
Molecular Weight
533.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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