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SUN-C5174

SUN-C5174 is a potent and selective 5-HT2 receptor antagonist (pA2=8.98) with antiplatelet activity. It inhibits serotonin-potentiated platelet aggregation in vitro (IC50=6.5-16 nM) and demonstrates protective efficacy in a murine model of acute pulmonary thromboembolism at oral doses ≥0.3 mg/kg.

Product Specifications

CAS Number

191592-36-6

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

CN1C2=C (C (=O) N (CCCN3CCN (CC3) C4=CC=C (F) C=C4) CC[C@@H]2O) C=C1

Molecular Formula

C22H29FN4O2

Molecular Weight

400.49

Storage Conditions

-20°C

Notes

For research use only.

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