SUN-C5174
SUN-C5174 is a potent and selective 5-HT2 receptor antagonist (pA2=8.98) with antiplatelet activity. It inhibits serotonin-potentiated platelet aggregation in vitro (IC50=6.5-16 nM) and demonstrates protective efficacy in a murine model of acute pulmonary thromboembolism at oral doses ≥0.3 mg/kg.
Product Specifications
CAS Number
191592-36-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
CN1C2=C (C (=O) N (CCCN3CCN (CC3) C4=CC=C (F) C=C4) CC[C@@H]2O) C=C1
Molecular Formula
C22H29FN4O2
Molecular Weight
400.49
Storage Conditions
-20°C
Notes
For research use only.
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