Tenofovir exalidex
Tenofovir exalidex (CMX 157) is a lipid-conjugated prodrug of tenofovir with potent activity against wild-type and drug-resistant HIV-1, HIV-2, and HBV. It demonstrates low nanomolar EC50 values in primary human PBMCs and macrophages, and has shown oral bioavailability with a favorable toxicity profile in preclinical studies, supporting its investigation as a broad-spectrum antiviral agent.
Product Specifications
CAS Number
911208-73-6
Product Name Alternative
HDP-Tenofovir, Antiviral, CMX 157, CMX157, CMX-157, Tenofovir exalidex
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.54% (May vary between batches)
Solubility
DMSO:Insoluble
Smiles
C ([C@H] (OCP (OCCCOCCCCCCCCCCCCCCCC) (=O) O) C) N1C=2C (N=C1) =C (N) N=CN2
Molecular Formula
C28H52N5O5P
Molecular Weight
569.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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