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Tenofovir exalidex

Tenofovir exalidex (CMX 157) is a lipid-conjugated prodrug of tenofovir with potent activity against wild-type and drug-resistant HIV-1, HIV-2, and HBV. It demonstrates low nanomolar EC50 values in primary human PBMCs and macrophages, and has shown oral bioavailability with a favorable toxicity profile in preclinical studies, supporting its investigation as a broad-spectrum antiviral agent.

Product Specifications

CAS Number

911208-73-6

Product Name Alternative

HDP-Tenofovir, Antiviral, CMX 157, CMX157, CMX-157, Tenofovir exalidex

Field of Research

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.54% (May vary between batches)

Solubility

DMSO:Insoluble

Smiles

C ([C@H] (OCP (OCCCOCCCCCCCCCCCCCCCC) (=O) O) C) N1C=2C (N=C1) =C (N) N=CN2

Molecular Formula

C28H52N5O5P

Molecular Weight

569.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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