Tigilanol tiglate
Tigilanol tiglate (EBC-46) is a small molecule activator of PKC/C1 domains that triggers immunogenic cell death via organelle stress, ATP depletion, and caspase activation. Its ability to enhance responses to immune checkpoint blockade has been demonstrated in preclinical in vivo models, supporting research in oncology and cancer immunotherapy.
Product Specifications
CAS Number
943001-56-7
Field of Research
Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction
Smiles
O (C ([C@H] (CC) C) =O) [C@@]12[C@@] (C1 (C) C) ([C@@]3 ([C@]4 ([C@] (CO) (O4) [C@@H] (O) [C@@]5 (O) [C@] ([C@@]3 (O) [C@H] (C) [C@H]2OC (/C (=C/C) /C) =O) (C=C (C) C5=O) [H]) [H]) [H]) [H]
Molecular Formula
C30H42O10
Molecular Weight
562.65
Storage Conditions
-20°C
Notes
For research use only.
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