TMI-1
TMI-1 (WAY-171318) is a potent, orally bioavailable dual inhibitor of ADAM17/TACE and matrix metalloproteinases (MMPs) . This small molecule has been shown to induce apoptotic cell death in breast cancer models, supporting its use in oncology research for studying tumor biology and therapeutic targets in both in vitro and in vivo settings.
Product Specifications
CAS Number
287403-39-8
Product Name Alternative
ADAM17, apoptosis, TMI 1, TMI1, TMI-1, WAY171318, WAY-171318, WAY 171318
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry
Purity
97.36% (May vary between batches)
Solubility
DMSO:35.9 mg/mL (90.09 mM)
Smiles
CC#CCOc1ccc (cc1) S (=O) (=O) N1CCSC (C) (C) [C@@H]1C (=O) NO
Molecular Formula
C17H22N2O5S2
Molecular Weight
398.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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