1-Methylpyrene

1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba

Product Specifications

CAS Number

[2381-21-7]

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-methylpyrene.html

Purity

99.51

Solubility

DMSO : 4.35 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1=C2C=CC3=CC=CC4=C3C2=C(C=C1)C=C4

Molecular Formula

C17H12

Molecular Weight

216.28

Precautions

H315, H319, H335

References & Citations

[1]Monien BH, et al. Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling. Chem Res Toxicol. 2008 Oct;21 (10) :2017-25. |[2]Hang Yu, et al. 1-Methylpyrene induces chromosome loss and mitotic apparatus damage in a Chinese hamster V79-derived cell line expressing both human CYP1A2 and sulfotransferase 1A1. Chem Biol Interact. 2020 Dec 1;332:109283.