VRT-532
VRT-532 (CFpot-532) is a small molecule CFTR modulator used in cystic fibrosis research. It has been shown in studies to upregulate arylsulfatase B (ARSB) activity, thereby reducing pathological accumulations of glycosaminoglycans like chondroitin-4-sulfate in cellular and animal models of CF.
Product Specifications
CAS Number
38214-71-0
Product Name Alternative
CFTR, CFpot532, CFpot-532, CFpot-532), F508del-CFTR, G551D-CFTR, VRT532, VRT-532, VRT 532
Field of Research
Pharmacology & Drug Discovery
Purity
99.88% (May vary between batches)
Solubility
DMSO:2.51 mg/mL (10.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4 mM)
Smiles
CC1=CC=C (O) C (=C1) C1=NNC (=C1) C1=CC=CC=C1
Molecular Formula
C16H14N2O
Molecular Weight
250.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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