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VU0422288

VU0422288 (ML396) is a potent orthosteric modulator selectively inhibiting mGluR4, mGluR7, and mGluR8, as demonstrated in calcium mobilization assays. This compound serves as a valuable research tool for investigating the pathophysiology of Rett syndrome (RTT) in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1630936-95-6

Product Name Alternative

ML 396, mGluR3, ML396, ML-396, VU0422288, VU-0422288, VU 0422288

Field of Research

Neuroscience

Purity

95.48% (May vary between batches)

Solubility

DMSO:3.61 mg/mL (10.02 mM)

Smiles

Clc1ccc (Oc2ccc (NC (=O) c3ccccn3) cc2Cl) nc1

Molecular Formula

C17H11Cl2N3O2

Molecular Weight

360.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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