VU0422288
VU0422288 (ML396) is a potent orthosteric modulator selectively inhibiting mGluR4, mGluR7, and mGluR8, as demonstrated in calcium mobilization assays. This compound serves as a valuable research tool for investigating the pathophysiology of Rett syndrome (RTT) in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1630936-95-6
Product Name Alternative
ML 396, mGluR3, ML396, ML-396, VU0422288, VU-0422288, VU 0422288
Field of Research
Neuroscience
Purity
95.48% (May vary between batches)
Solubility
DMSO:3.61 mg/mL (10.02 mM)
Smiles
Clc1ccc (Oc2ccc (NC (=O) c3ccccn3) cc2Cl) nc1
Molecular Formula
C17H11Cl2N3O2
Molecular Weight
360.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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