AMG-628
AMG-628 is a potent, ATP-competitive RAF kinase inhibitor effective against B-RAFV600E mutations. It inhibits proliferation and promotes cell cycle arrest and apoptosis in mutant colon and melanoma cell lines in vitro, supporting its investigation in targeted cancer therapy research.
Product Specifications
CAS Number
862269-73-6
Field of Research
Pharmacology & Drug Discovery
Smiles
O (C1=C2C (SC (NC (C) =O) =N2) =CC=C1) C=3C=C (N=CN3) N4CCN (C (C) C5=CC=C (F) C=C5) CC4
Molecular Formula
C25H25FN6O2S
Molecular Weight
492.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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