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AP-22161

AP-22161 is a selective Src SH2 domain inhibitor that binds conserved phosphotyrosine pocket cysteines. It disrupts Src SH2-mediated interactions and has been shown to inhibit osteoclast-mediated bone resorption in cellular assays, making it a useful research tool for studying bone metabolism and Src-related signaling pathways.

Product Specifications

CAS Number

268741-42-0

Smiles

N (C ([C@H] (CC1=CC (C=O) =C (C (O) =O) C=C1) NC (C) =O) =O) [C@@H]2C=3C (=CC (OCC4CCCCC4) =C (C (N) =O) C3) CCCC2

Molecular Formula

C32H39N3O7

Molecular Weight

577.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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