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AUY-954 free base

AUY-954 is a selective S1P1 receptor modulator effective in experimental autoimmune neuritis (EAN) models. It reduces T cell and B cell infiltration, macrophage presence, demyelination, and levels of IL-17 and MMP-9 in sciatic nerve tissue, demonstrating its utility for researching neuroinflammatory conditions.

Product Specifications

CAS Number

820240-77-5

Field of Research

Pharmacology & Drug Discovery

Smiles

C (F) (F) (F) C1=C (C=CC (=C1) C2=CC=3C (S2) =CC=C (CNCCC (O) =O) C3) C4=CC=CC=C4

Molecular Formula

C25H20F3NO2S

Molecular Weight

455.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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