AUY-954 free base
AUY-954 is a selective S1P1 receptor modulator effective in experimental autoimmune neuritis (EAN) models. It reduces T cell and B cell infiltration, macrophage presence, demyelination, and levels of IL-17 and MMP-9 in sciatic nerve tissue, demonstrating its utility for researching neuroinflammatory conditions.
Product Specifications
CAS Number
820240-77-5
Field of Research
Pharmacology & Drug Discovery
Smiles
C (F) (F) (F) C1=C (C=CC (=C1) C2=CC=3C (S2) =CC=C (CNCCC (O) =O) C3) C4=CC=CC=C4
Molecular Formula
C25H20F3NO2S
Molecular Weight
455.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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