BMS-695735
BMS-695735 is a benzimidazole-based IGF-1R inhibitor demonstrating broad-spectrum in vivo antitumor activity. Its pharmacological profile includes potent CYP3A4 inhibition, PXR-mediated CYP3A4 induction, low aqueous solubility, and high plasma protein binding. This compound is a valuable tool for investigating IGF-1R signaling in oncology research, both in cellular and animal models.
Product Specifications
CAS Number
1054315-48-8
Field of Research
Signal Transduction
Smiles
N (CCN1C=C (Cl) C=N1) C2=C (C=3NC=4C (N3) =C (C) C=C (C4) C5CCN (CCCF) CC5) C (=O) NC=C2
Molecular Formula
C26H31ClFN7O
Molecular Weight
512.02
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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