CHIR 98024
CHIR 98024 is a highly potent and selective inhibitor of GSK-3α and GSK-3β, exhibiting IC50 values in the sub-nanomolar range. It is widely used in research to investigate Wnt/β-catenin signaling, neuronal function, and metabolic studies in both cellular and animal models of diseases such as diabetes and neurodegeneration.
Product Specifications
CAS Number
556813-39-9
Product Name Alternative
CHIR-98024, CHIR 98014, CHIR 98024, CHIR98024, CHIR98014, CHIR-98014, p70 S6K, ischemic stroke, inhibit, Inhibitor, GSK-3α/β, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK3, GSK-3, S6 Kinase, S6Kinase
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
96.74% (May vary between batches)
Solubility
DMSO:6.88 mg/mL (14.15 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Nc1nc (NCCNc2ncc (-c3ncc[nH]3) c (n2) -c2ccc (Cl) cc2Cl) ccc1[N+] ([O-]) =O
Molecular Formula
C20H17Cl2N9O2
Molecular Weight
486.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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