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CHIR 98024

CHIR 98024 is a highly potent and selective inhibitor of GSK-3α and GSK-3β, exhibiting IC50 values in the sub-nanomolar range. It is widely used in research to investigate Wnt/β-catenin signaling, neuronal function, and metabolic studies in both cellular and animal models of diseases such as diabetes and neurodegeneration.

Product Specifications

CAS Number

556813-39-9

Product Name Alternative

CHIR-98024, CHIR 98014, CHIR 98024, CHIR98024, CHIR98014, CHIR-98014, p70 S6K, ischemic stroke, inhibit, Inhibitor, GSK-3α/β, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK3, GSK-3, S6 Kinase, S6Kinase

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

96.74% (May vary between batches)

Solubility

DMSO:6.88 mg/mL (14.15 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Nc1nc (NCCNc2ncc (-c3ncc[nH]3) c (n2) -c2ccc (Cl) cc2Cl) ccc1[N+] ([O-]) =O

Molecular Formula

C20H17Cl2N9O2

Molecular Weight

486.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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