CCG-257081
CCG-257081 (MRTF/SRF-IN-1) is a small molecule inhibitor targeting the Rho/MRTF/SRF pathway. It has demonstrated efficacy in preclinical models, such as reducing bleomycin-induced pulmonary fibrosis in mice, supporting its research applications in fibrosis and cancer prevention studies.
Product Specifications
CAS Number
1922098-90-5
Product Name Alternative
CCG257081, CCG-257081, CCG 257081, MRTF/SRF-IN-1, Rho, Ras
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.00% (May vary between batches)
Solubility
DMSO:50 mg/mL (105.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.55 mM)
Smiles
C (=O) (C=1C=C (C=C (F) C1) C=2C=CN=CC2) N3CC (C (NC4=CC=C (Cl) C=C4) =O) CC (F) (F) C3
Molecular Formula
C24H19ClF3N3O2
Molecular Weight
473.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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