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CCG-257081

CCG-257081 (MRTF/SRF-IN-1) is a small molecule inhibitor targeting the Rho/MRTF/SRF pathway. It has demonstrated efficacy in preclinical models, such as reducing bleomycin-induced pulmonary fibrosis in mice, supporting its research applications in fibrosis and cancer prevention studies.

Product Specifications

CAS Number

1922098-90-5

Product Name Alternative

CCG257081, CCG-257081, CCG 257081, MRTF/SRF-IN-1, Rho, Ras

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.00% (May vary between batches)

Solubility

DMSO:50 mg/mL (105.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.55 mM)

Smiles

C (=O) (C=1C=C (C=C (F) C1) C=2C=CN=CC2) N3CC (C (NC4=CC=C (Cl) C=C4) =O) CC (F) (F) C3

Molecular Formula

C24H19ClF3N3O2

Molecular Weight

473.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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