GSK1838705A
GSK1838705A is a potent, ATP-competitive small molecule inhibitor primarily targeting IGF-1R (IC50 2.0 nM), with additional activity against IR and ALK. It is a selective research tool used in vitro and in vivo to study signaling pathways in oncology, particularly in cancers driven by these receptors.
Product Specifications
CAS Number
1116235-97-2
Product Name Alternative
JNK3, inhibit, IGF-1R, IGF1R, Inhibitor, Insulin Receptor, GSK1838705A, GSK-1838705A, Cluster of differentiation 246, CD246, Anaplastic lymphoma kinase (ALK), Anaplastic lymphoma kinase, ALK, ALK tyrosine kinase receptor, RSK1, S6Kinase, S6 Kinase
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.89% (May vary between batches)
Solubility
DMSO:53.3 mg/mL (100.08 mM)
Smiles
CNC (=O) c1c (F) cccc1Nc1nc (Nc2cc3N (CCc3cc2OC) C (=O) CN (C) C) nc2[nH]ccc12
Molecular Formula
C27H29FN8O3
Molecular Weight
532.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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