Mouse Anti-Human CD11a/LFA-1a-LE/AF

The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C. <br>The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The biotin (BIOT) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The R-phycoerythrin (R-PE), allophycocyanin (APC), and Spectral Red (SPRD) conjugates are supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze! <br>The low endotoxin/azide-free antibody is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of PBS; aliquot and freeze upon receipt. <br>Protect conjugated forms from light. Reagents are stable for the period shown on the label if stored as directed.

Human CD11a (LFA-1 alpha)<br>CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 alpha), represents the 180 kDa integrin alpha L subunit which combines with the CD18 beta 2 integrin subunit to form the alpha L beta 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 alpha mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.1-5