Mouse Anti-Feline CD8-BIOT

The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C. <br> The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br> The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br> The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze! <br> Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.

Feline CD8, Mr 70 kDa (38/31 kDa under reducing conditions).<br>Feline CD8, a member of the immunoglobulin superfamily of cell surface receptors, is a type II transmembrane glycoprotein that is expressed as a heterodimer on the "suppressor/cytotoxic" subpopulation of peripheral T lymphocytes. It is present on approximately 63% of thymocytes, 9% of splenocytes, 20% of lymph node cells, and 15% of peripheral blood lymphocytes.1,2 CD8 functions as a co-receptor with MHC Class I-restricted T cell receptors in antigen recognition.