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Hamster Anti-Mouse TCRgd-UNLB

Product Specifications

CAS Number

9007-83-4

Reactivity

Mouse

Storage Conditions

The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 °C. <br>The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze! <br>The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze! <br>The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C. <br>Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.

Specificity

gamma delta T-cell receptor (TCR) complex<br>The TCR gamma delta heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of gamma delta TCRexpressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gamma delta + and have limited receptor diversity.1, 2 The TCR gamma delta heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.3 The monoclonal antibody UC7-13D5 is specific for the gamma delta heterodimer and plate-bound UC7-13D5 activates gamma delta TCR-bearing cells.4-7 This antibody does not react with alpha beta TCR-expressing T cells.

Short Name

[TCR gamma delta]

Available Sizes

Curated Selection

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