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Rat Anti-Mouse CD49e-FITC

Product Specifications

CAS Number

9007-83-4

Reactivity

Mouse

Storage Conditions

The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 °C. <br>The fluorescein (FITC) conjugate is supplied as 0.5 mg or 0.1 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze! <br>The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C. <br>Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.

Specificity

alpha 5 subunit of the integrin alpha 5 beta 1 fibronectin receptor<br>The monoclonal antibody 5H10-27 reacts with the alpha 5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines.^1-5 Soluble 5H10-27 antibody inhibits VLA-5-mediated functions in vitro.^1, 2-4, 6 Immobilized 5H10-27 has also been demonstrated to co-stimulate the proliferative response of CD8^+ T cells to plate-bound anti- CD3 monoclonal antibody.^3

Short Name

[CD49e/VLA-5]

Available Sizes

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