Rat Anti-Mouse CD2/LFA-2-LE/AF

The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C. <br>The fluorescein (FITC) conjugate is supplied as 0.5 mg or 0.1 mg in 1.0 mL of PBS/NaN3. Store at 2- 8 °C. <br>The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C. <br>The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze! <br>The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C. <br>Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.

Mouse CD2/LFA-2 (Mr 45-58 kDa)<br>CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules.^1 It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. ^1-3 In the mouse, CD2 is the receptor for CD48.^4 CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, Tcell signaling and intrathymic differentiation.^5-10

[CD2 antigen; T-cell surface antigen CD2; T-cell surface antigen CD2; LFA-3 receptor; lymphocyte antigen 37; T-cell surface antigen T11/Leu-5; CD2 antigen; LFA-2; LFA-3 receptor; Lymphocyte antigen 37; Ly-37; T-cell surface antigen T11/Leu-5]