Giripladib
Giripladib (PLA695, PLX-695) is a selective cPLA2 inhibitor that suppresses radiation-induced phosphorylation of ERK and Akt in endothelial cells. This small molecule is utilized in cardiovascular and radiation biology research, with applications in both in vitro cellular studies and in vivo experimental models.
Product Specifications
CAS Number
865200-20-0
Product Name Alternative
PLA695, PLA-695, PLA 695, cPLA2, Giripladib
Field of Research
Metabolism Research
Purity
99.64% (May vary between batches)
Solubility
DMSO:7.46 mg/mL (10.01 mM)
Smiles
C (N1C (CCNS (CC2=C (C (F) (F) F) C=CC=C2) (=O) =O) =C (CCCC3=CC=C (C (O) =O) C=C3) C=4C1=CC=C (Cl) C4) (C5=CC=CC=C5) C6=CC=CC=C6
Molecular Formula
C41H36ClF3N2O4S
Molecular Weight
745.25
Storage Conditions
-20°C
Notes
For research use only.
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