GNE-3476
GNE-3476 is a positive allosteric modulator (PAM) of the NMDA receptor, exhibiting differential activity across receptor subtypes with low efficacy at GluN2A, weak activity at GluN2B, and some AMPAR PAM activity. It is a research tool used in vitro to study synaptic plasticity, neuropharmacology, and the role of NMDA receptor subtypes in CNS function.
Product Specifications
CAS Number
951499-16-4
Smiles
O=C1N2C (=NC (CN (CC) C3=CC=CC=C3) =C1) SC (CCCC) =N2
Molecular Formula
C18H22N4OS
Molecular Weight
342.46
Storage Conditions
-20°C
Notes
For research use only.
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