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GNE-3476

GNE-3476 is a positive allosteric modulator (PAM) of the NMDA receptor, exhibiting differential activity across receptor subtypes with low efficacy at GluN2A, weak activity at GluN2B, and some AMPAR PAM activity. It is a research tool used in vitro to study synaptic plasticity, neuropharmacology, and the role of NMDA receptor subtypes in CNS function.

Product Specifications

CAS Number

951499-16-4

Smiles

O=C1N2C (=NC (CN (CC) C3=CC=CC=C3) =C1) SC (CCCC) =N2

Molecular Formula

C18H22N4OS

Molecular Weight

342.46

Storage Conditions

-20°C

Notes

For research use only.

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