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GNE-8324

GNE-8324 is a selective positive allosteric modulator of GluN2A-containing NMDA receptors. It potentiates NMDA receptor-mediated synaptic responses specifically in inhibitory neurons, making it a valuable research tool for studying synaptic physiology and neurological disorders in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1698901-76-6

Product Name Alternative

NMDA, GNE 8324, GNE8324, GNE-8324

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.68% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.65 mM) ; DMSO:80 mg/mL (232.95 mM)

Smiles

O=C1C=C (N=C2SC3=C (N12) CCC3) CN (C4=CC=C (F) C=C4) CC

Molecular Formula

C18H18FN3OS

Molecular Weight

343.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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