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12β-Hydroxyisocholic acid

12β-Hydroxyisocholic acid (Lagocholic acid) is a bile acid isomer that can be used in the study of bile acid metabolism[1].

Product Specifications

CAS Number

[71883-64-2]

Product Name Alternative

Lagocholic acid; 3α,7α,12β-Trihydroxy-5β-cholanic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Isomer; Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/12β-hydroxyisocholic-acid.html

Purity

99.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(O)=O)([C@@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C

Molecular Formula

C24H40O5

Molecular Weight

408.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhu P, et al. Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids. Anal Bioanal Chem. 2018 Aug;410 (21) :5287-5300.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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