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LCC-12 (formic)

LCC-12 formic is a dimer of metformin that targets mitochondrial copper (II), leading to a decrease in the NAD (H) pool and modulation of inflammatory responses. LCC-12 formic reduces inflammation in mouse models of bacterial and viral infections. LCC-12 formic also serves as a tool for investigating metabolic diseases through its effects on cell plasticity and epigenetic programming.

Product Specifications

CAS Number

3029253-76-4

UNSPSC

12352211

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lcc-12-formic.html

Purity

99.22

Smiles

O=CO.N=C(NC(NCCCCCCCCCCCCNC(NC(N)=N)=N)=N)N.O=CO

Molecular Formula

C18H40N10O4

Molecular Weight

460.57

References & Citations

[1]A druggable copper-signalling pathway that drives inflammation

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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