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LM-1685

LM-1685 is a potent and selective COX-2 inhibitor, demonstrating an IC50 of 0.65 μM in human monocytes and 4.3 μM in whole blood assays. This small molecule is a candidate for anti-inflammatory research, supporting investigations into COX-2-mediated pathways in both cellular and systemic models.

Product Specifications

CAS Number

416901-58-1

Product Name Alternative

COX-2, LM1685, LM-1685, LM 1685

Field of Research

Immunology & Inflammation, Neuroscience

Purity

98.16% (May vary between batches)

Solubility

Methanol:0.9 mg/mL (2.38 mM) ; DMSO:90 mg/mL (238.2 mM)

Smiles

C (N1C=2C (C=C1C (OC) =O) =CC (S (C) (=O) =O) =CC2) C3=CC=C (Cl) C=C3

Molecular Formula

C18H16ClNO4S

Molecular Weight

377.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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