XL413
XL-413 is an orally available, selective CDC7 kinase inhibitor that disrupts DNA replication initiation, leading to cell cycle arrest and apoptosis. It is used in cancer research to study replication stress and has shown antitumor activity in both cellular and animal models of CDC7-overexpressing cancers.
Product Specifications
CAS Number
1169558-38-6
Product Name Alternative
Cyclin dependent kinase, CDK, Cdc7, CK2, CaseinKinase, Casein Kinase, Inhibitor, inhibit, XL 413, XL413, XL-413, PIM1
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.40% (May vary between batches)
Solubility
DMSO:2.9 mg/mL (10.01 mM)
Smiles
O=C1C2=C (C=3C (O2) =CC=C (Cl) C3) NC (=N1) [C@@H]4CCCN4
Molecular Formula
C14H12ClN3O2
Molecular Weight
289.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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